On-going

  • Title -Identification of pathways involved in the regulation of CD45 expression in mesenchymal stem/stromal cells: Determination of its role in aging. Funded by Department of Biotechnology BioCare Scheme (2024-2027, Rs. 49.25 lakhs). PI – Dr. Madhurima Das; Mentor: Dr. Vaijayanti Kale; Nodal Officer: Dr. Anuradha Vaidya.
  • Title -Investigating the osteogenic potential of extracellular vesicles loaded injectable hydrogels. Funded by Department of Biotechnology (2021-2024, 36.50 lakhs). PI: Prasad Pethe, Co-PI: Dr. Vaijayanti Kale.
  • Title -Investigating the role of histone deubiquitinases in human pluripotent stem cell differentiation. Funded by Department of Biotechnology (2022-2024, 33.32 lakhs). PI: Dr. Prasad Pethe, Co-PI: Dr. Vaijayanti Kale.
  • Title-Investigating the role of Polycomb group (PcG) proteins in regulating Epithelial Mesenchymal transition (EMT) & fibrotic genes in endometrium of women with stage III-IV endometriosis. BT/PR43135/MED/97/609/2021. (2023-2026, 51.75 lakhs). PI: Dr Prasad Pethe, Co-PI: Dr. Vaijayanti Kale, Dr Anuradha Vaidya, Dr Prasad Bhanap.

Completed

  • Title - Molecular Analyses of extra-cellular vesicles isolated from bone marrow derived mesenchymal stromal cells treated with specific signalling modifiers and assessment of their effects on the fate of hematopoietic stem cells- Funded by Department of Biotechnology (2018-2021, 47.6 lakhs). PI – Dr. Anuradha Vaidya, Co-PI: Dr. Lalita Limaye, Dr. Srikanth Rapole and Dr. Vaijayanti Kale..
  • Title - Understanding the Activity of mechanonsensors -YAP and TAZ in differentiating human pluripotent stem cells. Funded by Department of Biotechnology (2019-2021, 22.87 lakhs). PI – Dr. Prasad Pethe, Co-I: Dr. Aparna Khanna..
  • Title -Synthesis of Novel polysaccharide based micro porous poly HIPE scaffolds for osteochondral tissue regeneration. Funded by Symbiosis International University (2019-2021, 10 lakhs). PI – Dr. Ganesh Ingavle..
  • Title - Neuronal regeneration using extra cellular vesicles isolated from murine bone marrow derived mesenchymal stromal cells: An in vitro study using cell model. Funded by Symbiosis International University (2020-2022, 10 lakhs). PI – Anuradha Vaidya.
  • Title - Biomimetic and Bilayered Interrpenetrating (IPN) hydrogel for osteochondral tissue regeneration. Funded by Department of Biotechnology (2019-2024, 42.5 lakhs). PI – Dr. Ganesh Ingavle.